- 专利标题： 3,6-DISUBSTITUTED-2-PYRIDINALDOXIME SCAFFOLDS
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申请号： EP19305185.1申请日： 2019-02-15
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公开(公告)号： EP3696170A1公开(公告)日： 2020-08-19
- 发明人: BAATI, Rachid , BROWN, Richard , DIAS, José , MARYAN-INSTONE, Alex , YERRI, Jagadeesh
- 申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , Université de Strasbourg
- 申请人地址： 3, rue Michel Ange 75016 Paris FR
- 专利权人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,Université de Strasbourg
- 当前专利权人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,Université de Strasbourg
- 当前专利权人地址： 3, rue Michel Ange 75016 Paris FR
- 代理机构： Lavoix
- 主分类号： C07D213/78
- IPC分类号： C07D213/78 ; C07D401/06 ; C07D473/02 ; C07D473/34 ; A61K31/44 ; A61K31/444 ; A61K31/52 ; A61K31/522 ; A61P25/00
摘要：
The present invention relates to a compound of formula (I), or one of its pharmaceutically acceptable salts:
wherein R1, R2 and -X-Y- have specific definitions.
It also relates to the use of such a compound as reactivator of acetylcholinesterase for treating organophosphorous nerve agents poisoning; and to a process for preparing it.
wherein R1, R2 and -X-Y- have specific definitions.
It also relates to the use of such a compound as reactivator of acetylcholinesterase for treating organophosphorous nerve agents poisoning; and to a process for preparing it.
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