- 专利标题： OSPA CHIMERAS AND USE THEREOF IN VACCINES
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申请号： EP19217974.5申请日： 2011-05-13
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公开(公告)号： EP3705133A2公开(公告)日： 2020-09-09
- 发明人: Crowe, Brian A. , Dr. Livey, Ian , O'Rourke, Maria , Schwendinger, Michael , Dunn, John J. , Luft, Benjamiin J.
- 申请人： Baxalta Incorporated , Baxalta GmbH , The Research Foundation for The State University of New York , Brookhaven Science Associates LLC
- 申请人地址： 1200 Lakeside Drive Bannockburn, IL 60015 US
- 专利权人： Baxalta Incorporated,Baxalta GmbH,The Research Foundation for The State University of New York,Brookhaven Science Associates LLC
- 当前专利权人： Baxalta Incorporated,Baxalta GmbH,The Research Foundation for The State University of New York,Brookhaven Science Associates LLC
- 当前专利权人地址： 1200 Lakeside Drive Bannockburn, IL 60015 US
- 代理机构： Maiwald Patent- und Rechtsanwaltsgesellschaft mbH
- 优先权： US33490110P 20100514
- 主分类号： A61K39/02
- IPC分类号： A61K39/02 ; C07K14/20
摘要：
The invention relates to the development of chimeric OspA molecules for use in against Lyme disease or borreliosis vaccine. More specifically, the chimeric OspA molecules comprise the proximal portion from one OspA serotype, together with the distal portion from another OspA serotype, while retaining antigenic properties of both of the parent polypeptides. The chimeric OspA molecules are delivered alone or in combination to provide protection against a variety of Borrelia genospecies.
公开/授权文献
- EP3705133B1 OSPA CHIMERAS AND USE THEREOF IN VACCINES 公开/授权日：2024-06-26
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