- 专利标题： BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF
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申请号： EP19740997.2申请日： 2019-01-11
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公开(公告)号： EP3741758A1公开(公告)日： 2020-11-25
- 发明人: ZHOU, Bing , LUO, Cheng , LI, Zizhou , YANG, Yaxi , CHEN, Shijie , DING, Hong , JIANG, Hualiang , QIAO, Gang , WANG, Xinjun , XIAO, Senhao
- 申请人： Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Suzhou Suplead Life Sciences Co., Ltd.
- 申请人地址： 555 Zu Chong Zhi Road Zhang Jiang Pudong, Shanghai 201203 CN
- 专利权人： Shanghai Institute of Materia Medica, Chinese Academy of Sciences,Suzhou Suplead Life Sciences Co., Ltd.
- 当前专利权人： Shanghai Institute of Materia Medica, Chinese Academy of Sciences,Suzhou Suplead Life Sciences Co., Ltd.
- 当前专利权人地址： 555 Zu Chong Zhi Road Zhang Jiang Pudong, Shanghai 201203 CN
- 代理机构： Petraz, Gilberto Luigi
- 优先权： CN201810040756 20180116; CN201811081153 20180917
- 国际公布： WO2019141131 20190725
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/53 ; A61P35/00
摘要：
The present invention relates to a bromodomain inhibitor. Provided are a compound represented by general formula I or a pharmaceutically acceptable salt, enantiomer, diastereomer, atropisomer, racemate, polymorph, solvate, or isotopically labeled compound (including deuterium substitution) thereof, a preparation method of the same, a pharmaceutical composition comprising the same, and a pharmaceutical use thereof.
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