发明公开
- 专利标题： STABILIZED THROMBIN
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申请号： EP20176522.9申请日： 2015-08-20
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公开(公告)号： EP3754017A3公开(公告)日： 2021-03-31
- 发明人: PILPEL, Yair , DORON, Sivan , ZHERDEV, Yuri , BYK-TENNENBAUM, Tamara
- 申请人： Omrix Biopharmaceuticals Ltd.
- 申请人地址： IL Rehovot 7610601 Bldg. 14, Weizmann Science Park PO Box 619
- 代理机构： Kirsch, Susan Edith
- 优先权： US201462039989 P 20140821
- 主分类号： C12N9/74
- IPC分类号： C12N9/74 ; C12N15/115 ; A61K38/48
摘要：
The present invention is directed to compounds, methods for stabilizing thrombin activity with a thrombin binding oligonucleotide and to stabilized thrombin. The thrombin binding oligonucleotide is capable of inhibiting thrombin activity whereby the inhibition can be reversed with an antisense oligonucleotide.
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