- 专利标题: NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST LUNG CANCER, INCLUDING NSCLC AND OTHER CANCERS
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申请号: EP20179381.7申请日: 2016-04-22
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公开(公告)号: EP3760225A3公开(公告)日: 2021-03-24
- 发明人: MAHR, Andrea , WEINSCHENK, Toni , SCHOOR, Oliver , FRITSCHE, Jens , SINGH, Harpreet , WAGNER, Claudia , LEIBOLD, Julia , SONG, Colette
- 申请人: Immatics Biotechnologies GmbH
- 申请人地址: DE 72076 Tübingen Paul-Ehrlich-Strasse 15
- 代理机构: Michalski Hüttermann & Partner Patentanwälte mbB
- 优先权: US201562152258 P 20150424
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; C07K14/47 ; C07K16/00 ; A61P35/00
摘要:
The present invention relates to peptides, especially the peptide of SEQ ID Nos. 24, 26 and 159, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor- associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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