- 专利标题： OXYSTEROL-STATIN COMPOUNDS FOR BONE GROWTH
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申请号： EP20213736.0申请日： 2018-05-09
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公开(公告)号： EP3831838A1公开(公告)日： 2021-06-09
- 发明人: PECKHAM, Steven M. , HARRINGTON, Roger E. , JACOBS, Jebrena C.
- 申请人： Warsaw Orthopedic, Inc.
- 申请人地址： US Warsaw, IN 46582 2500 Silveus Crossing
- 代理机构： Viering, Jentschura & Partner mbB Patent- und Rechtsanwälte
- 优先权： US201715599577 20170519
- 主分类号： C07J9/00
- IPC分类号： C07J9/00 ; C07J43/00 ; C07J7/00 ; C07J17/00 ; C07J51/00 ; A61K31/575 ; A61P19/00 ; A61P19/08 ; A61P19/10 ; A61K38/18
摘要：
Oxysterol-statin compounds and methods of synthesizing the same are provided for use in promoting osteogenesis, osteoinduction and/or osteoconduction. Methods of synthesizing in a single container OXY133-statin compounds having high yields and improved process safety are also provided. Methods for synthesizing OXY133-statin compounds that are stereoselective are also provided.
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