- 专利标题： MULTISPECIFIC MUTATED ANTIBODY FAB FRAGMENTS
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申请号： EP20168633.4申请日： 2012-07-06
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公开(公告)号： EP3872095A1公开(公告)日： 2021-09-01
- 发明人: KADOUCHE, Jean , MACH, Jean-Pierre , MICHIELIN, Olivier , ZOETE, Vincent , IWASZKIEWICZ, Justyna , CERUTTI, Martine , CHOBLET, Sylvie , GOLAY, Josée
- 申请人： Centre National de la Recherche Scientifique (CNRS) , University of Lausanne , Azienda socio-sanitaria territoriale Papa Giovanni XXIII , Kadouche, Jean
- 申请人地址： FR 75016 Paris 3, rue Michel Ange; CH 1005 Lausanne Office of Technology Transfer Rue de Bugnon 21; IT 24127 Bergamo Piazza OMS 1; FR 75013 Paris 62, boulevard Arago
- 代理机构： Regimbeau
- 优先权： EP11305872 20110707
- 主分类号： C07K16/46
- IPC分类号： C07K16/46 ; A61K39/395
摘要：
The invention relates to multispecific antibody constructs comprising Fab fragments having mutations at the interface of the CH1 and CL domains, said mutations preventing heavy chain/light chain mispairing.
公开/授权文献
- EP3872095B1 MULTISPECIFIC MUTATED ANTIBODY FAB FRAGMENTS 公开/授权日：2023-10-25
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