发明公开
- 专利标题： NOVEL IMIDAZOLE DERIVATIVE
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申请号： EP19888010.6申请日： 2019-11-20
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公开(公告)号： EP3884940A1公开(公告)日： 2021-09-29
- 发明人: TAKASHIMA, Hajime , MATSUDA, Yohei , OGATA, Yuya , SASAMOTO, Naoki , TSURUTA, Risa , USHIYAMA, Fumihito , UEKI, Kaori , TANAKA, Nozomi
- 申请人： Taisho Pharmaceutical Co., Ltd.
- 申请人地址： JP Tokyo 170-8633 24-1, Takada 3-chome Toshima-ku
- 代理机构： Hoffmann Eitle
- 优先权： JP2018218448 20181121
- 国际公布： WO2020105660 20200528
- 主分类号： A61K31/422
- IPC分类号： A61K31/422 ; A61K31/454 ; A61P31/04 ; C07D413/06 ; C07D413/14
摘要：
The present invention provides a new imidazole derivative represented by the following formula or a pharmaceutically acceptable salt thereof which exhibits potent antimicrobial activity based on a LpxC-inhibiting action against gram-negative bacteria such as Pseudomonas aeruginosa, Escherichia coli, and Klebsiella pneumoniae, and their drug-resistant strains.
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