- 专利标题： ISOLATED POLYPEPTIDE OF THE TOXIN A AND TOXIN B PROTEINS OF C. DIFFICILE AND USES THEREOF
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申请号： EP21157982.6申请日： 2011-09-05
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公开(公告)号： EP3895728A1公开(公告)日： 2021-10-20
- 发明人: ELLINGSWORTH, Larry , FLYER, David , TIAN, Jing-Hui , FUHRMANN, Steven , KLUEPFEL-STAHL, Stefanie , GLENN, Gregory , WESTRITSCHNIG, Kerstin
- 申请人： Valneva Austria GmbH , Valneva USA, Inc.
- 申请人地址： AT 1030 Vienna Campus Vienna Biocenter 3; US Gaithersburg, MD 20878 910 Clopper Road, Suite 160S
- 代理机构： Script IP Limited
- 主分类号： A61K39/08
- IPC分类号： A61K39/08 ; C07K14/33
摘要：
This present invention provides C-TAB.G5 and C-TAB.G5.1 isolated polypeptides comprising the receptor binding domains of C.difficile toxin A and toxin B as set forth in the amino acid sequences of SEQ ID NO:2 and SEQ ID NO:4. The C-TAB.G5 and C-TAB.G5.1 isolated polypeptides may be used to neutralize toxic effects of C.difficile toxin A and/or toxin B.
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