- 专利标题: BACILLUS SUBTILIS NATTO AND METHOD FOR PRODUCING PROTEIN MK-7
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申请号: EP19936410.0申请日: 2019-07-02
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公开(公告)号: EP3904501A1公开(公告)日: 2021-11-03
- 发明人: CHEN, Jiepeng , DUAN, Lili , HONG, Lin , CHEN, Yufan , CHEN, Hongrui , JI, Yeyu , CAI, Chunli , HU, Liusong , XU, Zhikai
- 申请人: Sungen Bioscience Co., Ltd.
- 申请人地址: CN Shantou, Guangdong 515071 Sungen Bio Park N1 Road Free Trade Zone
- 代理机构: Murgitroyd & Company
- 国际公布: WO2021000246 20210107
- 主分类号: C12N1/20
- IPC分类号: C12N1/20 ; C12P7/66 ; C07C46/10 ; C07C50/14 ; A61K31/122 ; A23L33/15 ; A23L33/115 ; A23L33/10 ; A23L29/30 ; A23L29/10 ; A23L29/00 ; C12R1/125
摘要:
Provided is a Bacillus subtilis natto strain ST-1008, deposited under the accession number CGMCC No. 17894. Also provided is a method for producing MK-7. The method comprises: culturing the Bacillus subtilis natto strain of CGMCC No. 17894 in a culture medium so as to produce MK-7 in the strain cell and the culture medium, and recovering and purifying MK-7 from the strain cell and the culture medium. Also provided are a MK-7 preparation, a MK-7 pure premix, and a pure MK-7.
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