- 专利标题： 6-OXO-1,6-DIHYDROPYRIDAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF
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申请号： EP20736089.2申请日： 2020-01-03
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公开(公告)号： EP3907218A1公开(公告)日： 2021-11-10
- 发明人: YANG, Fanglong , YU, Nan , CHI, Jiangtao , HE, Feng , TAO, Weikang
- 申请人： Jiangsu Hengrui Medicine Co., Ltd. , Shanghai Hengrui Pharmaceutical Co., Ltd.
- 申请人地址： CN Lianyungang, Jiangsu 222047 No. 7 Kunlunshan Road Economic and Technological Development Zone; CN Shanghai 200245 No.279 Wenjing Road Minhang District
- 代理机构： Potter Clarkson
- 优先权： CN201910567915 20190627
- 国际公布： WO2020140959 20200709
- 主分类号： C07D237/22
- IPC分类号： C07D237/22 ; C07C235/64 ; A61K31/166 ; A61K31/50 ; A61P25/00 ; A61P29/00
摘要：
A 6-oxo-1,6-dihydropyridazine derivative, a preparation method therefor and medical use thereof, in particular, a 6-oxo-1,6-dihydropyridazine derivative represented by general formula (I), a preparation method therefor, and a pharmaceutical composition containing the derivative, and use thereof as a Na V inhibitor and use thereof in the preparation of a drug for the treatment and/or prevention of pain and pain-related diseases. Each substituent in general formula (I) is the same as defined in the description.
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