- 专利标题： APJ RECEPTOR AGONISTS AND USES THEREOF
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申请号： EP21160055.6申请日： 2013-12-17
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公开(公告)号： EP3907237A1公开(公告)日： 2021-11-10
- 发明人: HOLDER, Jerry Ryan , SWAMINATH, Gayathri , MIRANDA, Leslie P. , ARAL, Jennifer , DOHERTY, Elizabeth M. , NIXEY, Thomas
- 申请人： Amgen Inc.
- 申请人地址： US Thousand Oaks, California 91320-1799 One Amgen Center Drive
- 代理机构： Lau, Sarah Jane
- 优先权： US201361779985 P 20130313
- 主分类号： C07K7/08
- IPC分类号： C07K7/08 ; C07K7/60
摘要：
The application is directed to APJ receptor agonist analogs having increased stability relative to the wild type apelin-13 and methods of using the agonist analogs. The analogs can be used, inter alia, in cardiac disorders such as heart failure.
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