- 专利标题： N-HETEROCYCLIC FIVE-MEMBERED RING-CONTAINING CAPSID PROTEIN ASSEMBLY INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF
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申请号： EP19911146.9申请日： 2019-09-27
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公开(公告)号： EP3915972A1公开(公告)日： 2021-12-01
- 发明人: ZHANG, Yinsheng , AO, Wangwei , LI, Yuan , WANG, Hui , SHEN, Hangzhou , NI, Jie , ZHANG, Huan , WU, Jie , ZHANG, Li , CAO, Kai , LU, Peng , LIU, Xushi , WANG, Jie , ZHAO, Tianxiao , GE, Xingfeng , LU, Dandan , CHEN, Shuo , MA, Xueqin , SHI, Wei , WANG, Xiaojin , XU, Hongjiang
- 申请人： Chia Tai Tianqing Pharmaceutical Group Co.,Ltd
- 申请人地址： CN Lianyungang, Jiangsu 222062 No. 369 Yuzhou South Road
- 代理机构： Potter Clarkson
- 优先权： CN201910073465 20190125
- 国际公布： WO2020151252 20200730
- 主分类号： C07D207/34
- IPC分类号： C07D207/34 ; A61K31/40 ; A61P31/20
摘要：
Provided is a compound of formula I or II, a stereoisomer, a tautomer, a geometrical isomer, a solvate, an active metabolite, a hydrate, a prodrug or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof, and the medical uses thereof in treating diseases benefiting from the capsid protein assembly inhibitor, particularly diseases caused by hepatitis B virus infection.
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