A cartridge assembly includes a channel member defining a cavity, and a staple cartridge including a cartridge body. A plurality of pushers disposed within the cartridge body, such that each pusher includes a staple supporting surface that defines a first concavity and a second concavity that are separated by a central radiused convexity. Each staple of a plurality of staples is received within one retaining slot of a plurality of retaining slots. Each staple of the plurality of staples includes a back span, wherein the shape of each staple of the plurality staples corresponds to the shape of the staple supporting surface of each of the plurality of pushers. An actuation sled can be moved within the cartridge body, into sequential engagement with the plurality of pushers to urge the plurality of staples through the plurality of retaining slots.