- 专利标题： TRUNCATED ROTAVIRUS VP4 PROTEIN AND APPLICATION THEREOF
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申请号： EP21194967.2申请日： 2016-05-20
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公开(公告)号： EP3981782A1公开(公告)日： 2022-04-13
- 发明人: GE, Shengxiang , LI, Tingdong , JIA, Lianzhi , LI, Yijian , XUE, Miaoge , ZENG, Yuanjun , ZHANG, Jun , XIA, Ningshao , PAN, Huirong
- 申请人： Xiamen University , Xiamen Innovax Biotech Co., Ltd.
- 申请人地址： CN Xiamen, Fujian 361005 No. 422, Si Ming Nan Road Siming District; CN Xiamen, Fujian 361022 1st Floor 50 Shan Bian Hong East Road Haicang District
- 代理机构： Vossius & Partner Patentanwälte Rechtsanwälte mbB
- 优先权： CN201510260020 20150521
- 主分类号： C07K14/14
- IPC分类号： C07K14/14 ; C12N15/46 ; A61K39/15 ; A61P31/14 ; A61K39/12
摘要：
The invention relates to a truncated rotavirus VP4 protein, a sequence encoding the same, a method for preparing the same, and a pharmaceutical composition and a vaccine comprising the protein, wherein the protein, the pharmaceutical composition and the vaccine are useful for preventing, alleviating or treating rotavirus infection and a disease caused by rotavirus infection, such as rotavirus gastroenteritis and diarrhea. The invention further relates to use of the protein in the manufacture of a pharmaceutical composition or a vaccine for preventing, alleviating or treating rotavirus infection and a disease caused by rotavirus infection, such as rotavirus gastroenteritis and diarrhea.
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