- 专利标题： IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVE USED AS TLR8 AGONIST
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申请号： EP20850028.0申请日： 2020-07-31
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公开(公告)号： EP4008720A1公开(公告)日： 2022-06-08
- 发明人: MIAO, Jianzhuang , WANG, Ce , ZHANG, Guoliang
- 申请人： BeiGene, Ltd.
- 申请人地址： KY Grand Cayman KY1-1108 C/o Mourant Governance Services (Cayman) Limited 94 Solaris Avenue, Camana Bay
- 代理机构： Mewburn Ellis LLP
- 优先权： CN202010075950 20200122
- 国际公布： WO2021023105 20210211
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/4188 ; A61P35/00
摘要：
Disclosed are an imidazo[2,1-f][1,2,4]triazin-4-amine derivative used as a TLR8 agonist or a stereoisomer thereof or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing same. Further disclosed is a method for treating cancers using the imidazo[2,1-f][1,2,4]triazin-4-amine derivative or the stereoisomer thereof or the pharmaceutically acceptable salt thereof as a TLR8 agonist.
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