- 专利标题： COMPOSITION FOR AUGMENTING STEMNESS AND USE THEREOF
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申请号： EP20874292.4申请日： 2020-10-08
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公开(公告)号： EP4043550A2公开(公告)日： 2022-08-17
- 发明人: KIM, Sung Hoon , BAEK, Ah Reum , CHO, Sung Rae , WOO, Jin Suk , KIM, Li La , KIM, Dae Hee
- 申请人： Genechem Inc. , University Industry Foundation, Yonsei University Wonju Campus , Industry-Academic Cooperation Foundation, Yonsei University
- 申请人地址： KR Daejeon 34025 A-201, 187, Techno 2-ro Yuseong-gu; KR Gangwon-do 26493 1 Yeonsedae-gil Heungeop-myeon Wonju-si; KR Seoul 03722 50, Yonsei-ro Seodaemun-gu
- 代理机构： J A Kemp LLP
- 优先权： KR20190124769 20191008
- 国际公布： WO2021071289 20210415
- 主分类号： C12N5/00
- IPC分类号： C12N5/00 ; C12N5/0775 ; C12N5/071 ; A61K35/28 ; A61K48/00
摘要：
The present application pertains to a sialyloligosaccharide for augmenting the stemness of stem cells and a use thereof and provides a composition for augmenting stemness of stem cells, a method of culturing stem cells in a medium containing a sialyloligosaccharide, a method of augmenting stemness of stem cells, a stem cell with augmented stemness, obtained by the method, and a cell therapy composition including the stem cells as an active ingredient. The composition or the method according to one or more embodiments may suppress the aging of stem cells and may maintain and augment stemness.
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