- 专利标题： METHOD FOR DETECTING UNDIFFERENTIATED CELLS
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申请号： EP20886654.1申请日： 2020-11-12
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公开(公告)号： EP4059960A1公开(公告)日： 2022-09-21
- 发明人: TANIGUCHI, Hideki , SEKINE, Keisuke , YASUI, Ryota
- 申请人： Public University Corporation Yokohama City University , EIKEN KAGAKU KABUSHIKI KAISHA
- 申请人地址： JP Yokohama-shi, Kanagawa 236-0027 22-2, Seto Kanazawa-ku; JP Tokyo 110-8408 4-19-9, Taito Taito-ku
- 代理机构： Hoffmann Eitle
- 优先权： JP2019207002 20191115
- 国际公布： WO2021095797 20210520
- 主分类号： C07K16/18
- IPC分类号： C07K16/18 ; C12N5/0735 ; C12N5/09 ; C12N5/10 ; C12Q1/6837 ; C12Q1/6841 ; C12Q1/6844 ; C12Q1/686 ; C12Q1/6862 ; C12Q1/6869 ; C12Q1/6872 ; C12Q1/6876
摘要：
The present invention provides a marker gene capable of detecting the undifferentiated cells that remain or become included in a differentiated cell population. Undifferentiated cells present in a differentiated cell population are detected by using at least one gene selected from the group consisting of LINC00678 and PRDM14 as an undifferentiation marker. A method of detecting undifferentiated cells; a method of using the gene as an undifferentiation marker; and a kit for detecting undifferentiated cells. A method of selecting an undifferentiated cell clone is also provided.
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