A display substrate, a display panel and a display apparatus are provided. The display substrate includes a first display region and a second display region, and a light transmittance of the first display region is greater than a light transmittance of the second display region. A plurality of sub-pixels located in the first display region includes a plurality of sub-pixel groups, each sub-pixel group includes a first sub-pixel and a second sub-pixel, the first pixel driving circuit includes a first sub-pixel driving circuit and a second sub-pixel driving circuit, the first sub-pixel driving circuit is configured to drive the first light-emitting device of the first sub-pixel to emit light, and the second sub-pixel driving circuit is configured to drive the first light-emitting device of the second sub-pixel to emit light. The first sub-pixel driving circuit includes at least a first reset transistor, the second sub-pixel driving circuit includes at least a second reset transistor, and the first reset transistor of the first sub-pixel driving circuit and the second reset transistor of the second sub-pixel driving circuit are at least partially shared with each other.