A display substrate and a manufacturing method therefor, and a display device. The display substrate comprises: a base substrate (101), a shift register unit (104), a first clock signal line (GCK) and a second clock signal line (GCB). The shift register unit (104) comprises an input circuit (1041), an output circuit (1043), a first control circuit (1042), a second control circuit (1045), and a voltage stabilizing circuit (1046). A first electrode (SD71) of a first noise reduction transistor (T7) of the second control circuit (1045) of the shift register unit (104) and a first electrode (SD81) of a voltage stabilizing transistor (T8) of the voltage stabilizing circuit (1046) of the shift register unit (104) are located at a first source/drain electrode layer, the first source/drain electrode layer comprises a first bridge electrode (E1), the first bridge electrode (E1) comprises a first portion (E11) and a second portion (E12), the first portion (E11) is connected to the first electrode (SD71) of the first noise reduction transistor (T7) and the first electrode (SD81) of the voltage stabilizing transistor (T8), and the second portion (E12) is connected to a gate electrode (G2) of a first control transistor (T2) of the first control circuit (1042). The wiring of the shift register unit (104) is simpler, which is beneficial for increasing the space utilization rate of the display substrate, such that it is easier to achieve a narrow frame of the display substrate.