- 专利标题: QUINAZOLINE COMPOUND AND PREPARATION METHOD, APPLICATION, AND PHARMACEUTICAL COMPOSTION THEREOF
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申请号: EP22213583.2申请日: 2017-12-26
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公开(公告)号: EP4169917A1公开(公告)日: 2023-04-26
- 发明人: XU, Heng , CHEN, Xiaoguang , LIN, Songwen , JI, Ming , JIN, Jing , WU, Deyu , WANG, Yangchun , LV, Yuanhao
- 申请人: Institute of Materia Medica, Chinese Academy of Medical Sciences
- 申请人地址: CN Beijing 100050 No. 1, Xian Nong Tan Street Xuanwu District
- 代理机构: EDP Patent Attorneys B.V.
- 优先权: CN201611214102 20161226
- 主分类号: C07D405/14
- IPC分类号: C07D405/14 ; C07D401/14 ; C07D401/04 ; A61K31/517 ; A61K31/5377
摘要:
The invention relates to quinazoline compounds, the preparation method, use, and the pharmaceutical composition thereof. The said quinazoline compounds, which are represented by Formula (I), are phosphatidylinositol 3-kinase (PI3K) inhibitors, and can be applied to prevent and/or treat PI3K activity-related diseases, such as cancer, immune diseases, cardiovascular diseases, viral infections, inflammation, metabolism/endocrine function disorders or neurological diseases.
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