Embodiments of this application provide a node handover method and a related device. A source donor node sends a handover request message to a target donor node, where the handover request message includes context information of an IAB node and context information of at least one terminal device. The source donor node receives a handover response message sent by the target donor node, where the handover response message includes an identifier of an accepted terminal device in the at least one terminal device and/or an identifier of a rejected terminal device in the at least one terminal device. In this way, the terminal device that is in the at least one terminal device connected to the IAB node and that is accepted by the target donor node may be handed over to the target donor node, so that the IAB node and the accepted terminal device are handed over to the target donor node together, and normal transmission of data of the accepted terminal device is ensured.