- 专利标题: MICROBIAL CONSORTIA PRODUCING DIPICOLINIC ACID AND METHODS FOR SELECTING MICROBES FOR CO-FORMULATION WITH CARRIERS
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申请号: EP22211714.5申请日: 2019-06-05
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公开(公告)号: EP4209581A1公开(公告)日: 2023-07-12
- 发明人: KENDIRGI, Frederic , GORDON, Benjamin
- 申请人: AMVAC Hong Kong Limited
- 申请人地址: HK Central Sheung Wan 11/F., Unit B, Winbase Centre Queen's Road
- 代理机构: Mewburn Ellis LLP
- 优先权: US201862681469 P 20180606
- 主分类号: C12N1/20
- IPC分类号: C12N1/20 ; C07H21/04 ; A01N63/00 ; C05F11/08 ; C12R1/01 ; C12R1/07 ; C12R1/465 ; C12R1/61 ; A01N63/22 ; A01N63/25 ; A01N63/27 ; A01N63/28 ; C12Q1/02 ; G01N33/573 ; A01N63/23
摘要:
Methods for selecting a microbe for co-formulation with a carrier are provided. In some examples, the methods include identifying a microbe that comprises one or more dipicolinic acid (DPA) synthase genes, a microbe that expresses one or more DPA synthase proteins, and/or a microbe that produces DPA; and selecting the microbe for co-formulation with a carrier. The methods optionally include co-formulating the selected microbe with the carrier. In some examples, the methods include detecting one or more DPA synthase genes or one or more DpaA and/or DpaB proteins in a microbe. In other examples, the methods include detecting DPA in a microbe or medium containing a microbe, for example, utilizing a fluorescence assay. Microbial compositions including one or more microbes that comprise one or more DPA synthase genes, express one or more DPA synthase proteins and/or produce DPA are also provided.
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