- 专利标题: BETA-STRAND TYPE CROSSLINKED PEPTIDE
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申请号: EP21886412.2申请日: 2021-10-29
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公开(公告)号: EP4238979A1公开(公告)日: 2023-09-06
- 发明人: HAYASHI, Kazuhiro , MATSUDA, Michiyuki
- 申请人: Xeno-Interface Inc. , Kyoto University
- 申请人地址: JP Kyoto city, Kyoto, 606-8386 Pressance Kyoto Sanjo Ohashi Higashiyamaen 207, 75-1 Shinmaruta-cho Nioumon-sagaru-futasujime-higashiiru Kawabata street, Sakyo-ku; JP Kyoto-shi, Kyoto 606-8501 36-1, Yoshida-honmachi Sakyo-ku
- 代理机构: Vossius & Partner Patentanwälte Rechtsanwälte mbB
- 优先权: JP2020183344 20201030
- 国际公布: WO2022092295 20220505
- 主分类号: C07K4/00
- IPC分类号: C07K4/00 ; A61K38/02
摘要:
The present disclosure provides a novel bridge peptide. The present disclosure provides a bridge peptide comprising a bridge moiety and a peptide moiety, wherein position β is tertiary or quaternary when the carbon at which the bridge moiety attaches to the peptide moiety is in position α. The present disclosure provides a novel bridge peptide, particularly a bridge peptide resulting from stably bridging a peptide that does not possess a hydrogen bond to induce or maintain a secondary structure, e.g., a peptide having a β-strand structure.
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