- 专利标题: ANTI-TUMOR PEPTIDE AND USE THEREOF
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申请号: EP21863087.9申请日: 2021-08-18
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公开(公告)号: EP4238982A1公开(公告)日: 2023-09-06
- 发明人: MATSUDA, Tadashi , ORITANI, Kenji , KITAI, Yuichi
- 申请人: NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
- 申请人地址: JP Kita-ku Sapporo-shi Hokkaido 060-0808 Kita 8-jyo Nishi 5-chome
- 代理机构: Prüfer & Partner mbB Patentanwälte · Rechtsanwälte
- 优先权: JP2020180811 20201028
- 国际公布: WO2022091531 20220505
- 主分类号: C07K7/08
- IPC分类号: C07K7/08 ; A61K38/08 ; A61K47/65 ; A61P35/00 ; C07K14/47 ; C07K14/82 ; C12N15/00
摘要:
The present invention provides a peptide that consists of an amino acid sequence with 20 or fewer residues containing at least one amino acid sequence selected from the group consisting of the amino acid sequence represented in SEQ ID NO: 1, the amino acid sequence represented in SEQ ID NO: 2 and the amino acid sequence represented in SEQ ID NO: 38, the peptide having an activity to inhibit proliferation of a tumor cell or having an activity to inhibit binding between an epidermal growth factor receptor and a signal-transducing adaptor family member-2 (STAP-2); a peptide with a cell-penetrating peptide added to a terminus of the above peptide with or without a linker sequence interposed between the cell-penetrating peptide and the terminus; and pharmaceutical compositions containing any of these peptides.
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