- 专利标题: MONOCLONAL ANTIBODIES AGAINST CLAUDIN-18 FOR TREATMENT OF CANCER
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申请号: EP23155995.6申请日: 2008-05-27
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公开(公告)号: EP4242236A3公开(公告)日: 2023-11-22
- 发明人: SAHIN, Ugur , TÜRECI, Özlem , BRANDENBURG, Gunda , USENER, Dirk
- 申请人: Astellas Pharma Inc. , TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
- 申请人地址: JP Chuo-ku Tokyo 103-8411 5-1, Nihonbashi-Honcho 2-Chome; DE 55131 Mainz Freiligrathstrasse 12
- 代理机构: Schnappauf, Georg
- 优先权: US93209907 P 20070529
- 主分类号: C07K16/30
- IPC分类号: C07K16/30 ; A61K39/395 ; A61P35/00 ; C12N5/12 ; C07K16/28 ; A61P35/04 ; A61P43/00 ; A61P37/04
摘要:
The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, cancer of the gallbladder, and the metastases thereof.
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