- 专利标题: COPOLYMER CONTAINING POLY(ETHYLENE GLYCOL) AND POLY(L-AMINO ACID DERIVATIVE), MICROPARTICLES THEREOF, AND USE THEREFOR IN PHARMACEUTICAL COMPOSITION
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申请号: EP21891854.8申请日: 2021-11-09
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公开(公告)号: EP4245792A1公开(公告)日: 2023-09-20
- 发明人: NAGASAKI, Yukio , LEE, Yaroslav , VONG, Binh Long , KODA, Yuta , DING, Yuanyuan
- 申请人: University of Tsukuba
- 申请人地址: JP Ibaraki 305-8577 1-1-1, Tennodai Tsukuba-shi
- 代理机构: Cabinet Nony
- 优先权: JP2020187688 20201111
- 国际公布: WO2022102608 20220519
- 主分类号: C08G69/02
- IPC分类号: C08G69/02 ; A61K31/785 ; A61K47/60 ; A61P1/16 ; C08G65/333
摘要:
An object of the present invention is to provide an assembled body of ornithine low in toxicity, effective even in oral administration and high in bioavailability. Another object of the present invention is to provide an ornithine assembled body which is effective in preventing or treating hepatic disorders. Another object is to provide a condensate obtained by introducing an acyl group or the like into an ornithine side chain amino group of polyethylene glycol-b-polyornithine, and to provide a novel assembled body not based on PIC.
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