- 专利标题： INHIBITION OF CYTOKINE-INDUCED SH2 PROTEIN IN NK CELLS
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申请号： EP23173594.5申请日： 2016-12-16
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公开(公告)号： EP4253412A2公开(公告)日： 2023-10-04
- 发明人: HUNTINGTON, Nicholas D. , NICHOLSON, Sandra E.
- 申请人： The Walter and Eliza Hall Institute of Medical Research
- 申请人地址： AU Melbourne, VIC 3052 1G Royal Parade, Parkville
- 代理机构： Hughes, Sean David
- 优先权： AU2015905220 20151216
- 主分类号： C07K16/22
- IPC分类号： C07K16/22
摘要：
The present invention relates to therapeutic and prophylactic methods based on inhibition of CIS in NK cells. In particular, the present invention relates to treating or preventing a NK-responsive condition by administering to a subject a CIS inhibitor, or administering CIS-inhibited NK cells. The invention further relates to methods for identifying a CIS inhibitor, and for determining a likelihood of cancer response to treatment with CIS inhibition
公开/授权文献
- EP4253412A3 INHIBITION OF CYTOKINE-INDUCED SH2 PROTEIN IN NK CELLS 公开/授权日：2023-11-22
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