This application relates to the technical field of image processing, and discloses an image sensor, a camera module, and an electronic device. The image sensor includes a pixel array and a plurality of amplifiers. The pixel array includes a plurality of pixel groups arranged in a row direction and/or a column direction, each pixel group includes a plurality of pixels of different colors, and each amplifier is in a one-to-one correspondence with each pixel, where an input end of a target amplifier is connected to an output end of a target pixel, an output end of the target amplifier is connected to a column line in which the target pixel is located, the target amplifier is any one of the plurality of amplifiers, and the target pixel is a pixel corresponding to the target amplifier.