- 专利标题： USE OF AMINO ACID SEQUENCES FROM MYCOBACTERIUM TUBERCULOSIS OR CORRESPONDING NUCLEIC ACIDS THEREOF FOR DIAGNOSIS AND PREVENTION OF TUBERCULAR INFECTION, DIAGNOSTIC KIT AND VACCINE THEREFROM
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申请号： EP23198546.6申请日： 2011-07-25
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公开(公告)号： EP4283303A3公开(公告)日： 2024-01-24
- 发明人: MARIANI, Francesca , AMICOSANTE, Massimo , COLIZZI, Vittorio , SALTINI, Cesare
- 申请人： QIAGEN Australia Holding Pty. Ltd.
- 申请人地址： AU Clayton VIC 3168 1894 Dandenong Road
- 代理机构： Carpmaels & Ransford LLP
- 优先权： ITRM20100411 20100723
- 主分类号： A61K38/16
- IPC分类号： A61K38/16 ; C07K14/35 ; C07K16/12 ; C12N5/00 ; C12Q1/68 ; G01N33/569 ; A61K38/10 ; G01N33/68
摘要：
Use of amino acid sequences from Mycobacterium tuberculosis or corresponding nucleic acids for diagnosis and prevention of tubercular infection, diagnostic kit and vaccine therefrom.
The present invention refers to the use of gene sequences or portions thereof characterized in that the same belong to the classes of in vitro and ex vivo induced, repressed or conserved genes in Mycobacterium tuberculosis currently infected human macrophages and to corresponding peptides or consensus peptides or proteins for the preparation of specific bio-markers for the diagnosis and prevention of active or latent disease.
The present invention refers to the use of gene sequences or portions thereof characterized in that the same belong to the classes of in vitro and ex vivo induced, repressed or conserved genes in Mycobacterium tuberculosis currently infected human macrophages and to corresponding peptides or consensus peptides or proteins for the preparation of specific bio-markers for the diagnosis and prevention of active or latent disease.
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