Use of a Crassocephalum rabens extract in improving skin condition is provided. Since the Crassocephalum rabens extract has activity in enhancing expression of collagen genes and/or of elastin genes, by administrating an effective amount of the Crassocephalum rabens extract or a composition containing the effective amount of the Crassocephalum rabens extract to an individual, levels of collagen and elastin in skin of the individual can be effectively increased, so as to improve skin texture and retard skin aging.