- 专利标题： METHODS FOR PRODUCING REGULATORY IMMUNE CELLS AND USES THEREOF
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申请号： EP23209126.4申请日： 2018-06-22
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公开(公告)号： EP4302768A2公开(公告)日： 2024-01-10
- 发明人: REZVANI, Katy , SHPALL, Elizabeth , BASAR, Rafet
- 申请人： Board Of Regents, The University Of Texas System
- 申请人地址： US Austin, TX 78701 210 West 7th Street
- 代理机构： J A Kemp LLP
- 优先权： US201762523637 P 20170622
- 主分类号： A61K35/17
- IPC分类号： A61K35/17
摘要：
Provided herein are methods for expanding populations of regulatory B cells comprising treating a population of B cells with IL-4 and CD40 ligand. Further provided herein are methods of expanding populations of regulatory T cells comprising expanding a population of T cells under Treg expansion conditions and selecting for CD9 + Tregs. Also provided herein are methods of treating immune disorders with the regulatory B cells and/or regulatory T cells.
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