- 专利标题： DRUG CONJUGATES COMPRISING ANTIBODIES AGAINST CLAUDIN 18.2
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申请号： EP23209136.3申请日： 2016-04-13
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公开(公告)号： EP4331578A3公开(公告)日： 2024-06-05
- 发明人: SAHIN, Ugur , TÜRECI, Özlem , WALTER, Korden , KREUZBERG, Maria , MITNACHT-KRAUS, Rita , LE GALL, Fabrice , JACOBS, Stefan
- 申请人： Astellas Pharma Inc. , TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
- 申请人地址： JP Chuo-ku Tokyo 103-8411 5-1, Nihonbashi-Honcho 2-Chome
- 专利权人： Astellas Pharma Inc.,TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
- 当前专利权人： Astellas Pharma Inc.,TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg- Universität Mainz gemeinnützige GmbH
- 当前专利权人地址： JP Chuo-ku Tokyo 103-8411 5-1, Nihonbashi-Honcho 2-Chome
- 代理机构： Müller, Christian Stefan Gerd
- 优先权： WO PCT/EP2015/058206 2015.04.15
- 分案原申请号： 16715583.7 2016.04.13
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; C07K16/30 ; A61K39/395 ; A61K47/68 ; A61P35/00 ; A61P35/04 ; A61K31/40
摘要：
The present invention provides anti-CLDN18.2 antibody-drug conjugates which are effective for treating and/or preventing cancer diseases associated with cells expressing CLDN18.2, including gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder and metastases thereof.
公开/授权文献
- EP4331578A2 DRUG CONJUGATES COMPRISING ANTIBODIES AGAINST CLAUDIN 18.2 公开/授权日：2024-03-06
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