- 专利标题： COMPLEMENT COMPONENT C5 IRNA COMPOSITIONS AND METHODS OF USE THEREOF
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申请号： EP24152344.8申请日： 2016-06-10
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公开(公告)号： EP4365291A2公开(公告)日： 2024-05-08
- 发明人: Borodovsky, Anna
- 申请人： Alnylam Pharmaceuticals, Inc.
- 申请人地址： US Cambridge, MA 02142 675 West Kendall Street, Henri. A. Termeer Square
- 专利权人： Alnylam Pharmaceuticals, Inc.
- 当前专利权人： Alnylam Pharmaceuticals, Inc.
- 当前专利权人地址： US Cambridge, MA 02142 675 West Kendall Street, Henri. A. Termeer Square
- 代理机构： Hoffmann Eitle
- 优先权： US 201562174933 P 2015.06.12
- 分案原申请号： 16732430.0 2016.06.10
- 主分类号： C12N15/113
- IPC分类号： C12N15/113
摘要：
The invention relates to iRNA, e.g., double stranded ribonucleic acid (dsRNA), compositions targeting the complement component C5 gene, and methods of using such iRNA, e.g., dsRNA, compositions to inhibit expression of C5 and to treat subjects having a complement component C5-associated disease, e.g., paroxysmal nocturnal hemoglobinuria.
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