- 专利标题： COMPOSITION FOR TREATING HYPERTROPHIC SCARS AND KELOIDS COMPRISING BENZHYDRYL THIOACETAMIDE COMPOUND AS ACTIVE INGREDIENT
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申请号： EP22853381.6申请日： 2022-08-01
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公开(公告)号： EP4368177A1公开(公告)日： 2024-05-15
- 发明人: KIM, Seong-Jin , KIM, Seon-Myung
- 申请人： Cellionbiomed Inc.
- 申请人地址： KR Daejeon 34013 A-407, Daedeok Biz Center 17, Techno 4-ro Yuseong-gu
- 专利权人： Cellionbiomed Inc.
- 当前专利权人： Cellionbiomed Inc.
- 当前专利权人地址： KR Daejeon 34013 A-407, Daedeok Biz Center 17, Techno 4-ro Yuseong-gu
- 代理机构： BCKIP Part mbB
- 优先权： KR 20210101359 2021.08.02
- 国际申请： KR2022011265 2022.08.01
- 国际公布： WO2023014003 2023.02.09
- 主分类号： A61K31/165
- IPC分类号： A61K31/165 ; A61P17/02 ; A61P43/00
摘要：
The present invention relates to a composition for treating hypertrophic scars and keloids, comprising a benzhydryl thioacetamide compound as an active ingredient. The benzhydryl thioacetamide compound inhibits cell proliferation and an increase in intracellular Ca2+ concentration, in fibroblasts, keratinocytes and vascular endothelial cells that are involved in skin fibrosis, and inhibits the synthesis of collagen, which is the extracellular matrix, and thus has the effect of effectively treating intractable hypertrophic scars and keloids.
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