- 专利标题: COMPOSITION FOR ORALLY ADMINISTERED FORMULATION CONTAINING GLP-1 ANALOGUE
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申请号: EP22842379.4申请日: 2022-07-08
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公开(公告)号: EP4371577A1公开(公告)日: 2024-05-22
- 发明人: CHOI, Go-Wun , CHO, Hyuk-Jun , IM, Ho-Taek , KIM, Yong-Il
- 申请人: Hanmi Pharm. Co., Ltd.
- 申请人地址: KR Hwaseong-si, Gyeonggi-do 18536 214 Muha-ro Paltan-myeon
- 专利权人: Hanmi Pharm. Co., Ltd.
- 当前专利权人: Hanmi Pharm. Co., Ltd.
- 当前专利权人地址: KR Hwaseong-si, Gyeonggi-do 18536 214 Muha-ro Paltan-myeon
- 代理机构: J A Kemp LLP
- 优先权: KR 20210091200 2021.07.12
- 国际申请: KR2022009915 2022.07.08
- 国际公布: WO2023287117 2023.01.19
- 主分类号: A61K47/54
- IPC分类号: A61K47/54 ; A61K9/00 ; A61K47/44 ; A61K47/14 ; A61K47/69 ; A61K38/22 ; A61K38/26 ; A61P3/10
摘要:
The present disclosure relates to a composition, for an orally administered formulation, containing a GLP-1 analogue and, particularly, to a pharmaceutical composition for oral administration comprising a hydrophobic ion-pair of a GLP-1 analogue and an oil phase, and a method for preparing the composition. The pharmaceutical composition for oral administration of the present disclosure forms an emulsion surrounding the hydrophobic ion-pair when exposed to a water phase, so as to be stably absorbed without being decomposed by means of digestive enzymes, and thus provides a pharmacological effect. Therefore, the present disclosure may be utilized as a pharmaceutical composition for oral administration.
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