发明公开
- 专利标题： CODON-OPTIMIZED OLIGONUCLEOTIDE FOR INDUCTION OF ELASTIN DE-NOVO SYNTHESIS IN MAMMALS
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申请号： EP22208908.8申请日： 2022-11-22
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公开(公告)号： EP4374870A1公开(公告)日： 2024-05-29
- 发明人: Avci-Adali, Meltem , Wendel, Hans-Peter , Golombek, Sonia
- 申请人： Eberhard Karls Universität Tübingen Medizinische Fakultät
- 申请人地址： DE 72074 Tübingen Geschwister-Scholl-Platz
- 专利权人： Eberhard Karls Universität Tübingen Medizinische Fakultät
- 当前专利权人： Eberhard Karls Universität Tübingen Medizinische Fakultät
- 当前专利权人地址： DE 72074 Tübingen Geschwister-Scholl-Platz
- 代理机构： Witte, Weller & Partner Patentanwälte mbB
- 主分类号： A61K38/39
- IPC分类号： A61K38/39 ; C07K14/78 ; C12N15/85
摘要：
The present invention relates to oligonucleotides for induction of elastin de-novo synthesis in mammals, a method of treatment of diseases and medical conditions associated with insufficient tissue elasticity, use of the oligonucleotide in such treatment, as well as pharmaceutical and cosmetical compositions comprising such oligonucleotide.
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