- 专利标题： A NOVEL IL33 FORM, MUTATED FORMS OF IL33, ANTIBODIES, ASSAYS AND METHODS OF USING THE SAME
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申请号： EP23219513.1申请日： 2016-03-30
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公开(公告)号： EP4374916A3公开(公告)日： 2024-08-28
- 发明人: COHEN, Emma, S , LOWE, David, C , BUTLER, Robin , SCOTT, Ian, C , VOUSDEN, Katherine, A , STRAIN, Martin, D , CARMEN, Sara , ENGLAND, Elizabeth, H , KEMP, Benjamin, P , REES, David, G , OVERED-SAYER, Catherine, L , MUSTELIN, Tomas, M , SLEEMAN, Matthew , HOUSLAY, Kirsty
- 申请人： MedImmune Limited
- 申请人地址： GB Cambridge Cambridgeshire CB21 6GH Milstein Building Granta Park
- 专利权人： MedImmune Limited
- 当前专利权人： MedImmune Limited
- 当前专利权人地址： GB Cambridge Cambridgeshire CB21 6GH Milstein Building Granta Park
- 代理机构： HGF
- 优先权： US 1562140913P 2015.03.31
- 分案原申请号： 20169253.0 2020.04.14;16712353.8 2016.03.30
- 主分类号： C07K16/24
- IPC分类号： C07K16/24 ; A61K39/395 ; A61K39/00 ; A01K67/027 ; C07K14/54 ; C07K14/715 ; A61P11/06 ; A01K67/0278
摘要：
The present invention provides isolated IL-33 proteins, active fragments thereof and antibodies, antigen binding fragments thereof, against IL-33 proteins. Also provided are methods of modulating cytokine activity, e.g., for the purpose of treating immune and inflammatory disorders.
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