- 专利标题： ANTI-HER3 ANTIBODY DRUG CONJUGATE, COMPOSITION THEREOF, AND USE THEREOF
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申请号： EP22869373.5申请日： 2022-09-16
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公开(公告)号： EP4389153A1公开(公告)日： 2024-06-26
- 发明人: CHEN, Tianxi , XU, Tongjie , TANG, Xiaoqi , FENG, Weiwei , ZHANG, Zhengping
- 申请人： CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
- 申请人地址： CN Lianyungang, Jiangsu 222062 No. 369 Yuzhou South Rd.,
- 专利权人： CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
- 当前专利权人： CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
- 当前专利权人地址： CN Lianyungang, Jiangsu 222062 No. 369 Yuzhou South Rd.,
- 代理机构： Müller Schupfner & Partner Patent- und Rechtsanwaltspartnerschaft mbB (Muc)
- 优先权： CN 2111085308 2021.09.16
- 国际申请： CN2022119214 2022.09.16
- 国际公布： WO2023041006 2023.03.23
- 主分类号： A61K47/68
- IPC分类号： A61K47/68 ; C07K16/28 ; C07D307/20 ; A61P35/00
摘要：
Provided is an anti-HER3 antibody drug conjugate, specifically comprising an antibody moiety, an intermediate linker moiety, and a cytotoxic drug moiety which are linked together. The provided antibody drug conjugate achieves excellent anti-tumor activity or/and better safety. The provided antibody drug conjugate can be used for the treatment of cancer.
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