An e-cigarette atomization device and e-cigarette are provided. The e-cigarette atomization device includes a housing, a liquid storage chamber, an upper cover, an atomization assembly, and a lower cover. The housing has an air outlet channel. The lower cover cooperates with and is connected to the housing. The lower cover has an air inlet channel. The upper cover and the atomization assembly are located inside the housing. The upper cover cooperates with the lower cover to form an accommodating cavity. The atomization assembly is located inside the accommodating cavity. An atomization chamber is formed between the atomization assembly and the lower cover. The atomization chamber is in communication with the air outlet channel and the air inlet channel respectively. The upper cover includes a sidewall. The sidewall has a ventilation channel. The ventilation channel runs through an inner surface and an outer surface of the sidewall, and is in communication with the liquid storage chamber and the atomization chamber respectively.