Invention Patent
JP2012036093A Method for manufacturing (s)-1-phenyl-1,2,3,4-tetrahydroisoquinoline
审中-公开
制备（S）-1-苯基-1,2,3,4-四氢喹啉的方法
- Patent Title: Method for manufacturing (s)-1-phenyl-1,2,3,4-tetrahydroisoquinoline
- Patent Title (中): 制备（S）-1-苯基-1,2,3,4-四氢喹啉的方法
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Application No.: JP2008318070Application Date: 2008-12-15
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Publication No.: JP2012036093APublication Date: 2012-02-23
- Inventor: MORI KOHEI , NISHIYAMA AKIRA
- Applicant: Kaneka Corp , 株式会社カネカ
- Assignee: Kaneka Corp,株式会社カネカ
- Current Assignee: Kaneka Corp,株式会社カネカ
- Priority: JP2008318070 2008-12-15
- Main IPC: C07D217/10
- IPC: C07D217/10
Abstract:
PROBLEM TO BE SOLVED: To inexpensively and efficiently produce (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline useful as an intermediate for a medicine and having high optical purity.SOLUTION: The (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline having the high optical purity can be produced by forming a salt from the easily available (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline having low optical purity and an inexpensive acid such as acetic acid and p-toluenesulfonic acid, and crystallizing the salt.
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