本发明可以含有载体，其通过二硫键交联的阳离子分量形成的聚合物载体，作为货物，和至少一种核酸分子（例如，用于作为佐剂使用）包括聚合物载体货物复杂， 和抗原从与感染相关的病原体;与自身免疫性疾病相关的抗原;过敏性或过敏性疾病相关的抗原从与或癌症或肿瘤疾病，或分别相关的抗原的至少一种抗原 对抗原的包含至少一种衍生物的片段，变体相关的，和药物组合物。 该药物组合物允许对抗原的适应性免疫应答有效诱导。 本发明特别，感染，变态反应，自身免疫性疾病和肿瘤或癌症疾病，该试剂盒，进一步的治疗提供了使用的药物组合物或试剂盒作为疫苗。

The present invention may contain as carrier, a polymeric carrier formed by a disulfide crosslinked cationic component, the cargo, and at least one nucleic acid molecule (e.g., for use as an adjuvant) comprising a polymeric carrier cargo complex, as well as antigen derived from a pathogen associated with the infection; antigen associated with autoimmune disease; antigen associated with allergy or allergic disease at least one antigen is selected from antigens associated with or cancer or tumor disease, or each for a fragment of said antigen, related variants, and pharmaceutical compositions comprising at least one derivative. The pharmaceutical composition allows for efficient induction of the adaptive immune response to said antigen. The present invention is particularly, infections, allergies, in the treatment of autoimmune diseases and tumor or cancer disease, the kit, and further provides the use of a pharmaceutical composition or kit as vaccines.