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Invention Patent
JP2021029130A 生体組織血管の試験装置 审中-公开

生体組織血管の試験装置
Abstract:
【課題】様々な生体内環境を模擬する拍動流及び定常流を生成するとともに、生体組織血管を良好な状態に保ち、構成部品及び実験条件の設定を簡素化することができる生体組織血管の試験装置を提供する。 【解決手段】拍動流及び定常流を生成する遠心ポンプ10と、生体組織血管1を培養液C中に浸漬状態で収容する培養槽20と、流体管路30と、を備え、流体管路30は、遠心ポンプ10と生体組織血管1の一端側とを直接連通する供給管路31と、生体組織血管1の他端側と培養槽20とを直接連通し、生体組織血管1の外側に培養液Cを循環させる循環管路32と、培養槽20と遠心ポンプ10とを直接連通し、生体組織血管1の外側を循環した培養液Cを排出させる戻り管路33と、を有している。 【選択図】図1
Abstract(English):

To provide a testing device of a biological tissue blood vessel which generates a pulsatile flow and a steady flow simulating various in vivo environments, and keeps the biological tissue blood vessel in a satisfactory state, and can simplify components and settings of experimental conditions.SOLUTION: A testing device comprises: a centrifugal pump 10 which generates a pulsatile flow and a steady flow; a culture tank 20 which houses a biological tissue blood vessel 1 in culture solution C in an immersed state; and a fluid pipeline 30. The fluid pipeline 30 has: a supply pipeline 31 which directly communicates the centrifugal pump 10 and one end side of the biological tissue blood vessel 1; a circulation pipeline 32 which directly communicates the other end side of the biological tissue blood vessel 1 and the culture tank 20, and circulates the culture solution C outside the biological tissue blood vessel 1; and a return pipeline 33 which directly communicates the culture tank 20 and the centrifugal pump 10, and discharges the culture solution C having circulated outside the biological tissue blood vessel 1.SELECTED DRAWING: Figure 1

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