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Invention Patent
JP2021161027A 経皮吸収抑制剤 审中-公开

経皮吸収抑制剤
Abstract:
【課題】脂質流動性成分が皮膚浸透することによる痛みやかゆみ等の刺激感や接触皮膚炎等の安全性上の問題を低減することができる経皮吸収抑制剤の提供。 【解決手段】アニオン界面活性剤と高級アルコールで形成するαゲルの層間および内部に、脂質流動化成分を内包した乳化粒子で構成されるαゲル構造体を有し、水中油型乳化物であることを特徴とする経皮吸収抑制剤。好ましくは、脂質流動化成分はメトキシケイヒ酸エチルヘキシルであることを特徴とする、経皮吸収抑制剤。 【選択図】図1
Abstract(English):

To provide a percutaneous absorption inhibitor that can reduce irritation feel such as pain and itch caused by the skin permeation of a lipid flowable component and safety problems such as contact dermatitis.SOLUTION: Provided is a percutaneous absorption inhibitor characterized by having an α-gel structure composed of emulsified particles involving a lipid flowable component between layers and inside of an α-gel formed of an anionic surfactant and a higher alcohol and being an oil-in-water emulsion. Preferably, the percutaneous absorption inhibitor is characterized in that the lipid flowable component is ethylhexyl methoxycinnamate.SELECTED DRAWING: Figure 1

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