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KR101608755B1 방사성 할로겐 표식 유기 화합물의 전구체 화합물 有权
放射性卤素标记有机化合物的前体化合物

방사성 할로겐 표식 유기 화합물의 전구체 화합물
摘要：
(과제) [F]FACBC를비롯한방사성할로겐표식아미노산화합물의표식전구체화합물로서사용할수 있고, 또한, 제조된방사성할로겐표식아미노산화합물중에메탄올이잔류되는일이없는신규아미노산유기화합물을제공한다. (해결수단) 하기식으로나타내어지는화합물.(식중, n은 0 또는 1∼4의정수, R은에틸치환기, 1-프로필치환기, 또는이소프로필치환기, X는할로겐치환기또는 -OR로나타내어지는기, R는직쇄또는분기쇄의탄소수 1∼10의할로알킬술폰산치환기, 탄소수 3∼12의트리알킬스타닐치환기, 플루오로술폰산치환기또는방향족술폰산치환기, R은보호기이다)로나타내어지는화합물.
摘要（英）：

(Problem) [18 F] can be used as a labeled precursor compound of a radioactive halogen-labeled amino acid compounds including FACBC, also, it provides a novel amino acid organic compound being free of methanol remaining in the produced radioactive halogen labeled amino acid compound.
(Solving means), the compound represented by the following formula.

(In the formula, n is 0 or an integer of 1 to 4, R 1 is ethyl substituent, 1-propyl substituent or isopropyl substituent, X is a halogen substituent or a group represented by -OR 2, R 2 is straight or branched chain haloalkyl having 1 to 10 carbon atoms in the sulfonic acid substituents, 3 to 12 carbon atoms of the carbonyl trialkyl star substituents, fluoro substituents, or an aromatic sulfonic acid substituent, R 3 is a protecting group), the compound represented by.

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