Invention Publication
KR1020060017747A 천식 및 다른 염증성 또는 면역성 이상들의 치료용ＣＣＲ３ 길항 활성을 갖는 2-페녹시- 및2-페닐설폰아마이드 유도체
失效 - Ended
具有CCR3拮抗活性的2-苯氧基和2-苯基磺酰胺衍生物用于治疗哮喘和其他炎症或免疫疾病
- Patent Title: 천식 및 다른 염증성 또는 면역성 이상들의 치료용ＣＣＲ３ 길항 활성을 갖는 2-페녹시- 및2-페닐설폰아마이드 유도체
- Patent Title (English): 2-phenoxy- and 2-phenylsulfomamide derivatives with ccr3 antagonistic activity for the treatment of asthma and other inflammatory or immunological disorders
- Patent Title (中): 具有CCR3拮抗活性的2-苯氧基和2-苯基磺酰胺衍生物用于治疗哮喘和其他炎症或免疫疾病
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Application No.: KR1020057017943Application Date: 2004-03-11
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Publication No.: KR1020060017747APublication Date: 2006-02-27
- Inventor: 리,잉푸 , 바콘,케빈 , 수기모토,히로미 , 후쿠시마,게이코 , 하시모토,겐타로 , 마루모,마키코 , 모리와키,토시야 , 누나미,노리코 , 츠노,나오키 , 얼반스,클라우스 , 요시다,나가히로
- Applicant: 액시킨 파마수티컬스 인코포레이티드
- Applicant Address: **** Carroll Canyon Road, Suite ***, San Diego, CA *****, U.S.A.
- Assignee: 액시킨 파마수티컬스 인코포레이티드
- Current Assignee: 액시킨 파마수티컬스 인코포레이티드
- Current Assignee Address: **** Carroll Canyon Road, Suite ***, San Diego, CA *****, U.S.A.
- Agent 특허법인필앤온지
- Priority: EP030062939 2003-03-24
- International Application: PCT/EP2004/002496 2004-03-11
- International Announcement: WO2004084898 2004-10-07
- Main IPC: C07D401/04
- IPC: C07D401/04 ; C07C311/37 ; C07D207/34
Abstract:
The present invention relates to a benzenesulfonamide derivative of formula (I), which is useful as an active ingredient of pharmaceutical preparations. The benzenesulfonamide derivatives of the present invention have CCR3 (CC type chemokine receptor) antagonistic activity, and can be used for the prophylaxis and treatment of diseases associated with CCR3 activity, in particular for the treatment of asthma, atopic dermatitis, allergic rhinitis and other inflammatory/immunological disorders. In said formula, X represents O or S; R4 represents formulae (a), (b), (c), (d), (e), (f), (g), (h), (i) or (j), the other substituents are as defined in claim 1.
Public/Granted literature
- KR101109296B1 천식 및 다른 염증성 또는 면역성 이상들의 치료용ＣＣＲ３ 길항 활성을 갖는 2-페녹시- 및2-페닐설폰아마이드 유도체 Public/Granted day:2012-02-08
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