Disclosed are a device, a method, and a system for for obtaining more than one biological fluid component using a back-flushable filter device, and reducing the red blood cell contamination. The device includes: a housing which comprises an inflow port and an outflow port, and limits a fluid path in between the inflow port and the outflow port; and a porous fibrous leukocyte removal filter with an upstream surface and a downstream surface, located on the housing after passing through the fluid path.