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KR20180033313A Ｌ-오르니틴 페닐 아세테이트, 및 이의 제조방법 审中-公开
- L-鸟氨酸乙酸苯酯及其制备方法

  • Patent Title: Ｌ-오르니틴 페닐 아세테이트, 및 이의 제조방법
  • Patent Title (English): KR20180033313A - L-ornithine phenyl acetate and methods of making thereof
  • Patent Title (中): - L-鸟氨酸乙酸苯酯及其制备方法
  • Application No.: KR20187008530
    Application Date: 2010-04-01
  • Publication No.: KR20180033313A
    Publication Date: 2018-04-02
  • Priority: US16667609 2009-04-03
  • Main IPC: A61K31/192
  • IPC: A61K31/192 ;  A61K31/198 ;  C07C57/46 ;  C07C229/26
Ｌ-오르니틴 페닐 아세테이트, 및 이의 제조방법
Abstract:
본발명은 L-오르니틴페닐아세테이트의결정형태및 이의제조방법에관한것이다. 본발명에따른 L-오르니틴페닐아세테이트의결정형태는형태 I, II, III, 및 V, 또는이의조합이다. 상기결정형태는간성뇌증과같은간질환을나타내는환자를치료하기위하여제조될수 있다. 또한본 발명은 L-오르니틴페닐아세테이트의제제화방법또는투여방법에관한것이다.
Abstract(Chinese):

本文公开了L-鸟氨酸苯乙酸酯的结晶形式及其制备方法。 在一些实施方案中，晶型可以是晶型I，II，III和V或其混合物。 可以配制结晶形式用于治疗患有肝病的受试者，例如肝性脑病。 因此，一些实施方案包括施用L-鸟氨酸苯乙酸酯的制剂和方法。

Abstract(English):

The present invention relates to a crystal form and a method of L- ornithine and phenylacetate. Crystal form of L- ornithine and phenylacetate in accordance with the present invention is form I, II, III, or V, or a combination thereof. The crystal forms can be prepared to treat a patient showing a liver, such as hepatic encephalopathy. The present invention further relates to a formulation or method of administration of L- ornithine and phenylacetate.

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