Invention Publication
- Patent Title: 튜불로신을 포함하는 암 예방 및 치료용 약제학적 조성물
- Patent Title (English): KR20180056366A - Pharmaceutical compositions comprising tubulosine for preventing or treating cancers
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Application No.: KR20170143573Application Date: 2017-10-31
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Publication No.: KR20180056366APublication Date: 2018-05-28
- Inventor: KIM BYUNG HAK , YE SANG KYU , LEE CHUNG GI
- Applicant: CYTUS H&B CO LTD
- Assignee: CYTUS H&B CO LTD
- Current Assignee: CYTUS H&B CO LTD
- Priority: KR20160154172 2016-11-18
- Main IPC: A61K31/4745
- IPC: A61K31/4745 ; A61K9/00 ; A61K31/437
Abstract:
본발명은튜불로신(tubulosine)을유효성분으로포함하는암 치료용약제학적조성물에관한것이다. 본발명의조성물에서튜불로신은백혈병과림프종세포주에서 JAK 촉매활성을억제함으로써, 구조적으로활성화된사이토카인-유도성 JAK3 신호전달을모두강력하게억제하므로, 활성 JAK-매개암 세포의생존및 증식을억제하는제제로서유용하게사용될수 있다.
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