- 专利标题： Antibody evolution immunogens
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申请号： US14427581申请日： 2013-09-12
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公开(公告)号： US10004800B2公开(公告)日： 2018-06-26
- 发明人: Barton F. Haynes , Hua-Xin Liao , Rebecca M. Lynch , Tongqing Zhou , Feng Gao , Scott Boyd , George M. Shaw , Beatrice H. Hahn , Thomas B. Kepler , Bette T. Korber , Peter Kwong , John Mascola
- 申请人： Duke University , Los Alamos National Security, LLC , The Trustees of The University of Pennsylvania , Trustees of Boston University , The United States of America as Represented by The Secretary of the Department of Health and Human Services , The Board of Trustees of the Leland Stanford Junior University
- 申请人地址： US NC Durham US NM Los Alamos US PA Philadelphia US MA Boston US DC Washington US CA Palo Alto
- 专利权人： Duke University,Los Alamos National Security, LLC,The Trustees of The University of Pennsylvania,Trustees of Boston University,The United States of America as Represented by The Secretary of the Department of Health and Human Services National Institutes of Health Office of Technology Transfer,The Board of Trustees of the Leland Stanford Junior University
- 当前专利权人： Duke University,Los Alamos National Security, LLC,The Trustees of The University of Pennsylvania,Trustees of Boston University,The United States of America as Represented by The Secretary of the Department of Health and Human Services National Institutes of Health Office of Technology Transfer,The Board of Trustees of the Leland Stanford Junior University
- 当前专利权人地址： US NC Durham US NM Los Alamos US PA Philadelphia US MA Boston US DC Washington US CA Palo Alto
- 代理机构： Wilmer Cutler Pickering Hale and Dorr LLP
- 国际申请： PCT/US2013/000210 WO 20130912
- 国际公布： WO2014/042669 WO 20140320
- 主分类号： A61K39/21
- IPC分类号： A61K39/21 ; A61K39/12 ; C07K14/005 ; C12N7/00 ; A61K39/00
摘要：
The present invention relates, in general, to HIV-1 and, in particular, to broadly neutralizing HIV-1 antibodies, and to HIV-1 immunogens and to methods of using such immunogens to induce the production of broadly neutralizing HIV-1 antibodies in a subject (e.g., a human).
公开/授权文献
- US20150366961A1 ANTIBODY EVOLUTION IMMUNOGENS 公开/授权日：2015-12-24
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